Our approximately 25 strong process R&D (PRD) staff work in five dedicated process laboratories equipped with standard laboratory equipment including staff operated HPLCs (Agilent 1100/1200 VWD). Via our ARD (analytical research and development) laboratory, our PRD staff have access to chiral HPLC, achiral/chiral GC, GCMS (Agilent), LCMS (Agilent), polarimetery, FTIR, Karl Fisher titration, UV-Vis, stability Chamber, LOD, and ROI analysis, which are all operated by ARD staff with proper quality control. Our ARD staff also conduct chiral and achiral HPLC and GC analytical method development. DSC/TGA/X-Ray (single crystal/powder diffraction) analysis is conducted at ScinoPharm Taiwan or the Shanghai Institute of Organic Chemistry (SIOC).

Reactions are conducted at scales between 5 mL and 20 L. Our PRD staff are led by experienced group leaders and managers. Each group leader is responsible for one R&D laboratory.

In process R&D we develop free-to-operate generic API processes followed by technology transfer to our Taiwan parent (SPT) for cGMP production. We also develop free-to-operate processes for API intermediates as well as key intermediate scale-up development for CRO customers (via ScinoPharm Taiwan). We have more than 7 patents pending as a result of our process development projects at this facility.

In our analytical R&D laboratory we conduct instrument qualification and calibration, analytical method development and validation. We set up raw material specifications, in process control methods, product specifications and conduct product stability studies. The following equipment is utilized by this department:

• LCMS (Agilent 6120, single quadrapole, ESI)
• GCMS (Agilent 7890A GC/5975C MSD)
• 2 x Agilent 1100 HPLC  (2xDAD; 1xRID)
• 5 X Agilent 1200 HPLC (VWD)
• Agilent 1200 HPLC (DAD)
• Shimadzu GC-2010 AF GC with TurboMatri x 16 Headspace sampler
• Agilent 7890 FID/ECD GC with Agilent 70 Headspace sampler
• 2 x Agilent 6890 FID GC 
• Audolph Autopol III polarimeter
• Nicolet FTIR Avator 360
• Metrohm 831 Karl Fisher titrator
• Mettler Toledo DL32 Karl Fisher titrator
• Mettler Toledo HG 63 Halogen moisture analyzer
• Metrohm 794 Auto-titrator
• Agilent 8453 UV-Vis Spectrophotometer
• GIANT stability chamber

• 2 x 50 L glass-lined reactor
• 2 x 30 L glass-lined reactor
• 2 x 20 L glass reactor
• 2 x 10 L glass reactor
• 2 x 30 L glass extractor
• 2 x 30 L stainless steel hydrogenator
• 50 L Rotavap
• 50 L Pressure filter with agitator
• 3 x Vacuum oven dryer
• Separate utility heating and cooling (-15 °C to 130 °C)
• Utility 10 mmHg vacuum
• 1 x 10 L S316 Centrifuge
• 1 x 300 mm S316 Cymbals filter

Our hydrogenation laboratory is equipped with the following hydrogenators:

• 1 x 300 mL hydrogenator (up to 200 bar; r.t. to 350 °C)
• 1 x 1 L hydrogenator (up to 220 bar; r.t. to 350 °C)
• 1 x 2 L hydrogenator (up to 100 bar; r.t. to 300 °C)
• 2 x 30 L stainless steel hydrogenator (up to 6 bar; r.t. to 95 °C)

A leased production facility, fitted with reactors, a control room and a QC laboratory and about 400 square meter of warehouse was commissioned in late 2006. This facility is located in Taicang, 40 minutes drive from Kunshan, and is fully operated by our own production staff. This facility is dedicated to production of API key intermediates. These intermediates are then used by ScinoPharm Taiwan as starting materials for the GMP production of APIs. The facility is equipped with more than 25 reactors with a total reactor volume of more than 31 m³. The configuration allows more than three concurrent production lines. IPC (in process control) utilizes dedicated Agilent 1100 HPLCs and Agilent 4890 GCs.

• 2 x 3000 L glass-lined (0 to 200 °C)
• 7 x 2000 L glass-lined (0 to 200 °C)
• 4 x 1000 L glass-lined/stainless steel reactor (0 to 200°C)
• 2 x 1000 L stainless steel low temperature reactor (N_{2 (l)} cooling system)
• 3 x 500 L glass-lined/stainless steel reactor (0 to 200 °C)
• 1 x 300 L glass-lined reactor (r.t. to 200 °C)
• 1 x 500 L glass-lined reactor (r.t. to 200 °C; electric heated)
• 1 x 300 L glass-lined reactor (r.t. to 200 °C; electric heated)
• 1 x 200 L glass-lined reactor (0 to 200 °C)
• 1 x 1000 L Double-cone vacuum dryer (G/L)
• 1 x 1000 L Double-cone vacuum dryer (stainless steel)
• 1 x 2.5 m 3  Air-blower dryer with trays (steam heated)
• 1 x 48 trays vacuum dryer (steam heated)
• 2 x Centrifuge (0.6 and 0.8 m diameter)
• 2 x Centrifuge (1.0 m diameter)
• 2 x Pulverizer (stainless steel)
• 2 x stainless steel chromatography columns (20 cm ID x 2 m length)